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KMID : 0383820140770020081
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Tuberculosis and Respiratory Diseases
2014 Volume.77 No. 2 p.81 ~ p.84
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A Case of Venlafaxine-Induced Interstitial Lung Disease
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Oh Se-Rim
Cha Seung-Ick
Kim Hye-Ra
Kim Min-Jung
Choi Sun-Ha
Seo Hye-Won
Park Tae-In
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Abstract
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A patient treated with venlafaxine for major depression developed an interstitial lung disease (ILD) with the characteristic clinical, radiological and pathological features of chronic hypersensitivity pneumonitis. A high resolution computed tomography scan demonstrated ground glass opacity, mosaic perfusion with air-trapping and traction bronchiectasis in both lungs. The pathological findings were consistent with a nonspecific interstitial pneumonia pattern. Clinical and radiological improvements were noted after the discontinuation of venlafaxine and the administration of a corticosteroid. This report provides further evidence that the anti-depressant venlafaxine can cause ILD.
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KEYWORD
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Hypersensitivity, Pneumonia, Lung Disease, Interstitial, Venlafaxine
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